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CD200 Protein (CD200) (AA 31-232) (hIgG-His-tag)

This Recombinant CD200 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7596333
发货至: 中国

Quick Overview for CD200 Protein (CD200) (AA 31-232) (hIgG-His-tag) (ABIN7596333)

抗原

See all CD200 蛋白
CD200

蛋白类型

Recombinant

宿主

  • 23
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  • 1
小鼠

资源

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Baculovirus infected Insect Cells

应用范围

SDS-PAGE (SDS)

纯度

> 95% by SDS-PAGE
  • 产品特性

    AA 31-232

    标记

    This CD200 protein is labelled with hIgG-His-tag.

    序列

    QVEVVTQDER KALHTTASLR CSLKTSQEPL IVTWQKKKAV SPENMVTYSK THGVVIQPAY KDRINVTELG LWNSSITFWN TTLEDEGCYM CLFNTFGSQK VSGTACLTLY VQPIVHLHYN YFEDHLNITC SATARPAPAI SWKGTGTGIE NSTESHFHSN GTTSVTSILR VKDPKTQVGK EVICQVLYLG NVIDYKQSLD KG

    内毒素水平

    < 1 EU per 1ug of protein (determined by LAL method)
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    CD200

    别名

    CD200

    背景

    CD200, also known as OX-2 membrane glycoprotein isoform 1, is one of the immunoglobulin superfamily. It plays an important role in anti-tumor immunity through interaction with its receptor, and overexpression of this protein effects on malignancies as well as on cancer stem cells. In T cells, this protein functions as a co-stimulatory effect that is independent of the CD28 pathway. It also plays an important role on myeloid cell regulation that is suggested by restricted expression of its receptor. Studies of this protein in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Recombinant mouse CD200, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

    分子量

    49.5 kDa (441aa)

    NCBI登录号

    NP_034948
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