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MitTx Toxin (Active) 蛋白

This Native MitTx Toxin protein is expressed in Micrurus tener tener (Texas coral snake).
产品编号 ABIN7887288
发货至: 中国
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Quick Overview for MitTx Toxin (Active) 蛋白 (ABIN7887288)

抗原

MitTx Toxin

蛋白类型

Native

生物活性

Active

宿主

Micrurus tener tener

资源

Micrurus tener tener (Texas coral snake)

纯度

≥98 % (HPLC)
  • 原理

    MitTx Toxin

    序列

    MitTx-α subunit:
    QIRPAFCYED PPFFQKCGAF VDSYYFNRSR ITCVHFFYGQ CDVNQNHFTT MSECNRVCHG
    MitTx-β subunit:
    NLNQFRLMIK CTNDRVWADF VDYGCYCVAR DSNTPVDDLD RCCQAQKQCY DEAVKVHGCK PLVMFYSFEC RYLASDLDCS GNNTKCRNFV CNCDRTATLC ILTATYNRNN HKIDPSRCQ

    特异性

    Toxin target: ASIC1-containing acid-sensing ion channels (ASICs) 

    Biological Activity Comment

    MitTx toxin activates ASIC1-containing channels1,2.
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  • 应用备注

    Antigen Preadsorption Control: 20 nM

    说明

    Electrophysiology

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial and dissolve by gently tapping, tilting, or rolling the vial. Avoid vigorous vortexing, a brief, light vortex of 1-2 seconds is acceptable if necessary. The product is readily soluble in high-quality pure water at micromolar to millimolar concentrations (typically 100 μM to 1  mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x the final working concentration. Divide the stock solution into small, single-use aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh working solutions just before use. Avoid multiple freeze-thaw cycles to maintain optimal biological activity.

    缓冲液

    Lyophilized from double distilled water (ddH2O). May contain residual trifluoroacetate (TFA).

    注意事项

    Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom,Avoid multiple freeze-thaw cycles to maintain optimal biological activity,Avoid vigorous vortexing. protect from moisture

    储存条件

    -20 °C

    储存方法

    The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.
  • 抗原

    MitTx Toxin

    背景

    An activator of ASIC1-containing channels

    分子量

    20.84 kDa (i± subunit, 7.104 kDa and i² subunit, 13.736 kDa)

    UniProt

    G9I930, G9I929
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