IGF2BP3 Protein (AA 1-579) (His tag)
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北京 101111
Quick Overview for IGF2BP3 Protein (AA 1-579) (His tag) (ABIN7564935)
抗原
See all IGF2BP3 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-579
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标记
- This IGF2BP3 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant Igf2bp3 Protein expressed in mammalian cells.
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序列
- MNKLYIGNLS DHAGPADLES VFKDAKIPVA GPFLVKTGYA FVDCPDEGWA LKAIEALSGK MELHGKPMEV EHSVPKRQRI RKLQIRNIPP HLQWEVLDSL LVQYGVVESC EQVNTDSETA VVNVTYSSKD QARQALDKLN GFQLENFTLK VAYIPDETAA QQNPSPQLRG RRGPGQRGSS RQASPGSVSK QKPCDLPLRL LVPTQFVGAI IGKEGATIRN ITKQTQSKID VHRKENTGAA EKSITILSTP EGTSAACKSI LEIMHKEAQD IKFTEEIPLK ILAHNNFVGR LIGKEGRNLK KIEQDTDTKI TISPLQELTL YNPERTITVK GSVETCAKAE EEIMKKIRES YENDIASMNL QAHLIPGLNL NALGLFPPTS GMPPPTSGPP STLTPPYPQF EQSETETVHL FIPALSVGAI IGKQGQHIKQ LSRFAGASIK IAPAEAPDAK VRMVIITGPP EAQFKAQGRI YGKIKEENFV SPKEEVKLEA HIRVPSFAAG RVIGKGGKTV NELQSLSSAE VVVPRDQTPD ENDQVVVKIT GHFYACQVAQ RKIQEILTQV KQHQQQKALQ SGPPQSRRK Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3) (AA 1-579) protein (His tag)
custom-made IGF2BP3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3) (AA 1-579) protein (GST tag)IGF2BP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3) (AA 284-579) protein (His tag)IGF2BP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))
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别名
- Igf2bp3
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背景
- Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (mIMP-3) (IGF-II mRNA-binding protein 3) (VICKZ family member 3),FUNCTION: RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability (By similarity). Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation (By similarity). Binds to beta-actin/ACTB and MYC transcripts (By similarity). Increases MYC mRNA stability by binding to the coding region instability determinant (CRD) and binding is enhanced by m6A-modification of the CRD (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. {ECO:0000250|UniProtKB:O00425, ECO:0000269|PubMed:15753088}.
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分子量
- 63.6 kDa
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UniProt
- Q9CPN8
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AlphaFold
- Q9CPN8
抗原
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