FBXO38 Protein (AA 1-1194) (His tag)
custom-made
FBXO38
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 抗原 See all FBXO38 蛋白
- FBXO38 (F-Box Protein 38 (FBXO38))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-1194
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This FBXO38 protein is labelled with His tag.
- 原理
- Custom-made recombinant Fbxo38 Protein expressed in mammalian cells.
- 序列
- MGPRKKSAKV CVMDSEVAEE MTADEEKDYM NQLSHEVLCH IFRYLPLQDI MCMECLSRKL KEAVTLYLRV VRVVDLCAGR WWEYMPSGFT DSSFLTLLKK MPDVEQLYGL HPRYLERRRV RGQEAFSIPG VLEALQACPN LVGVETSHLE LVESIWTYMP HVHILGKFRN RNGAFPIPPE NKLKIPIGAK IQTLHLVGVN VPEIPCIPML RHLYMKWVRL TKPQPFKDFL CISLRTFVMR NCAGPTNSLK YVPLVTGLAS ARNLEHLEMV RVPFLGGLIQ HVVEDSWRSG GFRNLHTIVL GACKNALEVD LGYLIITAAR RLHEVRIQPS LTKDGVFSAL KMAELEFPQF ETLHLGYVDE FLLQSRMANA DLVKYGLADV VENPGIITDI GMKAVNEVFS CIKYLAIYNC PHLHNPYNWI SDHSRWMRLV DINLVRCHAL KLDSFGQFVE LLPSLEFISL DQMFREPPKG CARVGLSAGT GIGVSSALVS NQNSNNDNDN NAPNNNANLH DNNHHHPDDS DDDNDFRPDL QAGEAQFAAD ALNEMEDMVQ EDGELVAESG NGMPAHNREV LPVDADEEQA GPSGLQRVVK PTPIADHDSE SDDEEDSLEL QEVWAPKNGT RRYSEREEKT GDSGQSRETA VSGKGKTPLR KRCNNSHQTG QAKPFPLEES SCEKGCQVTS EQIKADMKAA RDVSEKKKSK DVYPSCSSSS SSTAASTAGN ASSPSTASQS PDFARTVTSS GSSEPSPPEV DVSRQCVCSP GGSEDSEAME EGDAESSVCP RCCCLRPQES QRRTGRCSDE ERPSTSRACV VNGADGTRSA FSFRTLPQGG SSGPAHDERT NGSGCGATGE DRRGSSQPES CDVQSNEDYP RRPLTRARSR LSHVPLISES EVAKTKPCHA MKRKRTADKS TSTSDPVIED DHVQVLVLKS KNLVGVTMTN CGITDLVLKD CPKMMFIHAT RCRVLKHLKV ENAPIVNRFD YAQCKKLNMD QVLDQILRMP PERNRIIYLR PMQQVDTLTL EQKLFSGPYP YHICIIHEFS NPPNVRNKVR IRNWMDTIAN INQELIKYEF FLEATRTEED LKKYPKYPWG REIYTLEGVV DGAPYSMISD FPWLRSLRTA EPNSFARYDF EDDEESTIYA PRRKGQLSAD ICMETIGEEI SEMRQMKRGI FQRVVAIFIH YCDVNGEPVE DDYI Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product FBXO38 蛋白
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F-Box Protein 38 (FBXO38) (AA 1-1188) protein (His tag)
custom-made FBXO38 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
F-Box Protein 38 (FBXO38) (AA 1-426) protein (GST tag)FBXO38 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- FBXO38 (F-Box Protein 38 (FBXO38))
- 别名
- Fbxo38 (FBXO38 产品)
- 背景
- F-box only protein 38 (Modulator of KLF7 activity) (MoKA),FUNCTION: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of PDCD1/PD-1, thereby regulating T-cells-mediated immunity (PubMed:30487606). Required for anti-tumor activity of T-cells by promoting the degradation of PDCD1/PD-1, the PDCD1-mediated inhibitory pathway being exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:30487606). May indirectly stimulate the activity of transcription factor KLF7, a regulator of neuronal differentiation, without promoting KLF7 ubiquitination (PubMed:14729953, PubMed:16990251). {ECO:0000269|PubMed:14729953, ECO:0000269|PubMed:16990251, ECO:0000269|PubMed:30487606}.
- 分子量
- 133.9 kDa
- UniProt
- Q8BMI0
- AlphaFold
- Q8BMI0
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