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KCNN2 Protein (AA 1-839) (His tag)

This Recombinant KCNN2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7563466
发货至: 中国
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Quick Overview for KCNN2 Protein (AA 1-839) (His tag) (ABIN7563466)

抗原

See all KCNN2 蛋白
KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))

蛋白类型

Recombinant

宿主

  • 4
  • 1
小鼠

资源

  • 2
  • 2
  • 1
HEK-293 Cells

纯度

> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

质量等级

custom-made
  • 产品特性

    AA 1-839

    标记

    This KCNN2 protein is labelled with His tag.

    原理

    Predefined custom protein recombinant Kcnn2 Protein expressed in mammalian cells.

    序列

    MPIVLVRPTN RTRRLDSTGA GMGPSSHQQQ ESPLPTITHC AGCTTAWSPC SFNSSDMETP LQFQRGFFPE QPPPPPRSSH LHCQQQQQSQ DKPCAPFAPL PHPHHHPHLA HQQPGSGGSS PCLRCNSCAS SGAPAAGAGA GDNLSLLLRT SSPGGAFRTR TSSPLSGSSC CCCCSSRRGS QLNVSELTPS SHASALRQQY AQQPASASQY HQCHSLQPAT SPTGSLGSLG SGPPLSHHHH HPHPAHHQHH QPQARRESNP FTEIAMSSCR YNGGVMRPLS NLSSSRRNLQ EMDSEAQPLQ PPASVVGGGG GASSPSAAAA ASSSAPEIVV SKPEHNNSNN LALYGTGGGG STGGGGGGSG HGSSSGTKSS KKKNQNIGYK LGHRRALFEK RKRLSDYALI FGMFGIVVMV IETELSWGAY DKASLYSLAL KCLISLSTII LLGLIIVYHA REIQLFMVDN GADDWRIAMT YERIFFICLE ILVCAIHPIP GNYTFTWTAR LAFSYAPSTT TADVDIILSI PMFLRLYLIA RVMLLHSKLF TDASSRSIGA LNKINFNTRF VMKTLMTICP GTVLLVFSIS LWIIAAWTVR ACERYHDQQD VTSNFLGAMW LISITFLSIG YGDMVPNTYC GKGVCLLTGI MGAGCTALVV AVVARKLELT KAEKHVHNFM MDTQLTKRVK NAAANVLRET WLIYKNTKLV KKIDHAKVRK HQRKFLQAIH QLRSVKMEQR KLNDQANTLV DLAKTQNIMY DMISDLNERS EDFEKRIVTL ETKLETLIGS IHALPGLISQ TIRQQQRDFI ETQMENYDKH VSYNAERSRS SSRRRRSSST APPTSSESS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

    特异性

    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

    产品特性

    Key Benefits:
    • Predefined custom protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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  • 应用备注

    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The buffer composition is at the discretion of the manufacturer.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -80 °C

    储存方法

    Store at -80°C.

    有效期

    12 months
  • 抗原

    KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))

    别名

    Kcnn2

    背景

    Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2),FUNCTION: Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:11557517, PubMed:13679367, PubMed:14657188). Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. {ECO:0000269|PubMed:11557517, ECO:0000269|PubMed:13679367, ECO:0000269|PubMed:14657188}.

    分子量

    91.6 kDa

    UniProt

    P58390

    AlphaFold

    P58390
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