SULT2A1 Protein (AA 1-285) (His tag)
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北京 101111
Quick Overview for SULT2A1 Protein (AA 1-285) (His tag) (ABIN7563422)
抗原
See all SULT2A1 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-285
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标记
- This SULT2A1 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant Sult2a1 Protein expressed in mammalian cells.
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序列
- MMSDYNWFEG IPFPAISYQR EILEDIRNKF VVKEEDLLIL TYPKSGTNWL IEIVCLIQTK GDPKWIQTVP IWNRSPWIET DIGYSALINK EGPRLITSHL PIHLFSKSFF SSKAKAIYLV RNPRDILVSG YFFWGNTNLV KNPGSLGTYF EWFLKGNVLF GSWFEHVRGW LSMREWDNFL VLYYEDIKKD TKGTIKKICD FLGKNLGPDE LDLVLKYSSF QAMKENNMSN FSLIKEDQVT NGLKLMRKGT IGDWKNHFTV AQAEAFDKVF QEKMAGFPPG IFPWE Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- SULT2A1 (Sulfotransferase Family, Cytosolic, 2A, Dehydroepiandrosterone (DHEA)-Preferring, Member 1 (SULT2A1))
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别名
- Sult2a1
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背景
- Sulfotransferase 2A1 (ST2A1) (EC 2.8.2.2) (Bile salt sulfotransferase 1) (EC 2.8.2.14) (Hydroxysteroid sulfotransferase) (ST),FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands (PubMed:12639899). Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism (By similarity). In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols (By similarity). {ECO:0000250|UniProtKB:P15709, ECO:0000250|UniProtKB:Q06520, ECO:0000269|PubMed:12639899}.
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分子量
- 33.2 kDa
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UniProt
- P52843
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AlphaFold
- P52843
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途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process
抗原
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