ST6GALNAC1 Protein (AA 1-526) (His tag)
This Recombinant ST6GALNAC1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7561813
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for ST6GALNAC1 Protein (AA 1-526) (His tag) (ABIN7561813)
抗原
See all ST6GALNAC1 蛋白
ST6GALNAC1
(ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 1 (ST6GALNAC1))
蛋白类型
Recombinant
宿主
小鼠
资源
HEK-293 Cells
纯度
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
质量等级
custom-made
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产品特性
- AA 1-526
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标记
- This ST6GALNAC1 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant St6galnac1 Protein expressed in mammalian cells.
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序列
- MTRYCRGLSQ RQAFLLLTVL ALLFILLFVV KDPRAKDSRC QFIWKNDASA QENQQKAEPQ VPIMTLSPRV HNKETTSVSS KDLKKQEREA VQGEQAEGKE KRKLETIRPA PENPQSKAEP AAKTPVSEHL DKLPRAPGAL STRKTPMATG AVPAKKKVVQ ATKSPASSPH PTTRRRQRLK ASEFKSEPRW DFEEEYSLDM SSLQTNCSAS VKIKASKSPW LQNIFLPNIT LFLDSGRFTQ SEWNRLEHFA PPFGFMELNQ SLVQKVVTRF PPVRQQQLLL ASLPTGYSKC ITCAVVGNGG ILNDSRVGRE IDSHDYVFRL SGAVIKGYEQ DVGTRTSFYG FTAFSLTQSI LILGRRGFQH VPLGKDVRYL HFLEGTRDYE WLEAMFLNQT LAKTHLSWFR HRPQEAFRNA LDLDRYLLLH PDFLRYMKNR FLRSKTLDTA HWRIYRPTTG ALLLLTALHL CDKVSAYGFI TEGHQRFSDH YYDTSWKRLI FYINHDFRLE RMVWKRLHDE GIIWLYQRPQ SDKAKN Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 1 (ST6GALNAC1) (AA 1-600) protein (His tag)
custom-made ST6GALNAC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- ST6GALNAC1 (ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 1 (ST6GALNAC1))
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别名
- St6galnac1
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背景
- Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.3.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (ST6GalNAcI) (Sialyltransferase 7A) (SIAT7-A),FUNCTION: Protein sialyltransferase specifically expressed in goblet cells that plays a key role in intestinal host-commensal homeostasis (PubMed:35303419). Conjugates sialic acid with an alpha-2-6 linkage to N-acetylgalactosamine (GalNAc) glycan chains linked to serine or threonine in glycoproteins (PubMed:10788794). Catalyzes the formation of the sialyl-Tn (S-Tn) antigen, an antigen found in intestinal goblet cells (PubMed:35303419). Protein sialylation in globlet cells is essential for mucus integrity and is required to protect the intestinal mucus against excessive bacterial proteolytic degradation (PubMed:35303419). {ECO:0000269|PubMed:10788794, ECO:0000269|PubMed:35303419}.
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分子量
- 60.7 kDa
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UniProt
- Q9QZ39
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AlphaFold
- Q9QZ39
抗原
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