Majin (AA 1-256) protein (His tag)
This Recombinant Majin protein is expressed in HEK-293 Cells.
产品编号 ABIN7561158
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Majin (AA 1-256) protein (His tag) (ABIN7561158)
抗原
Majin
蛋白类型
Recombinant
宿主
小鼠
资源
HEK-293 Cells
纯度
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
质量等级
custom-made
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产品特性
- AA 1-256
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标记
- His tag
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原理
- Predefined custom protein recombinant Majin Protein expressed in mammalian cells.
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序列
- MSLKPFTYPF PETRFLHAGP NVYKFKIRYG NSIRGEEIED KEVIVQELED SIRAVLANMD SLQPFVTEHF IVFPYKSKWE RVSHLKFKHG ESILTPYPFV FTLYIEMKWF AEDLPSGKPA DDIPLELVLA ETEAEEATMR KWKRKLMEEP SSPSRQGPHR AKMETSSEAS SNKKPLKESK RSTDEEAQQE YQDTPASNAI AVKEQDAALG HGLQGLVVPP LQHSSPPPPK EPGARGFLGF LSALFPFRYF FKKSGQ Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- Majin
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背景
- Membrane-anchored junction protein,FUNCTION: Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the complex, MAJIN acts as the anchoring subunit to the nucleus inner membrane. MAJIN shows DNA-binding activity, possibly for the stabilization of telomere attachment on the nucleus inner membrane. {ECO:0000269|PubMed:26548954}.
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分子量
- 29.2 kDa
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UniProt
- Q9D992
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AlphaFold
- Q9D992
抗原
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