SOCS4 Protein (AA 1-436) (His tag)
Quick Overview for SOCS4 Protein (AA 1-436) (His tag) (ABIN7560132)
抗原
See all SOCS4 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-436
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标记
- This SOCS4 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant Socs4 Protein expressed in mammalian cells.
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序列
- MAENNSKNVD VRPKTSRSRS ADRKDGYVWS GKKLSWSKKS ESCSESEAIG TVENVEIPLR SQERQLSCSS IELDLDHSCG HRFLGRSLKQ KLQDAVGQCF PIKNCSGRHS PGLPSKRKIH ISELMLDKCP FPPRSDLAFR WHFIKRHTVP MSPNSDEWVS ADLSERKLRD AQLKRRNTED DIPCFSHTNG QPCVITANSA SCTGGHITGS MMNLVTNNSI EDSDMDSEDE IITLCTSSRK RNKPRWEMEE EILQLEAPPK FHTQIDYVHC LVPDLLQISN NPCYWGVMDK YAAEALLEGK PEGTFLLRDS AQEDYLFSVS FRRYSRSLHA RIEQWNHNFS FDAHDPCVFH SPDITGLLEH YKDPSACMFF EPLLSTPLIR TFPFSLQHIC RTVICNCTTY DGIDALPIPS PMKLYLKEYH YKSKVRLLRI DVPEQQ Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) protein (His tag)
custom-made SOCS4 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) protein (GST tag)SOCS4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Suppressor of Cytokine Signaling 4 (SOCS4) protein (His tag)SOCS4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
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别名
- Socs4
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背景
- Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7),FUNCTION: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR (By similarity). {ECO:0000250}.
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分子量
- 49.9 kDa
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UniProt
- Q91ZA6
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AlphaFold
- Q91ZA6
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途径
- JAK/STAT Signaling, EGFR Signaling Pathway
抗原
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