Quick Overview for N4BP3 Protein (AA 1-537) (His tag) (ABIN7559188)
抗原
N4BP3
(NEDD4 Binding Protein 3 (N4BP3))
蛋白类型
Recombinant
宿主
小鼠
资源
HEK-293 Cells
纯度
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
质量等级
custom-made
产品特性
AA 1-537
标记
This N4BP3 protein is labelled with His tag.
原理
Predefined custom protein recombinant N4bp3 Protein expressed in mammalian cells.
序列
MATTSGPAGI AMGSVGSLLE RQDFSPEELR AALAGSRGSR QPDGLLRKGL GQREFFSYLH LPKKDGKTTK RAPRNEPDYA TLYYREHPRA GDFSKTSLPE RGRFDKCRIR PSVFKPPVGS GKGFLSMQSL AAHKGQKLWR SNGSLHTLAC HPPLSPGPRA SQARAQLLHA LSLDEGGPEP SLSDSSSGGS FGRSPGTGPS PFSSSLGHIN HLGGSLDRAP RSPKESGPLA VLSCLPEPPP PYEFSCPTTE EVAVLPEARE ELKRDLGDQD VSNSFTQVLE ERQRLWLSEL KRLYVERLHE VAQKAERSER NLQLQLFMAQ QEQRRLRKEL RAQQGLAPEP RTSGSSMEAD PNARPEEEAR WEVCQKTAEI SLLKQQLREA QAELAQKLAE IFSLKTQLRG SRAQAQAQDA ELARLREAVH SLQEQAPREE APGSCETDDC KSRGLLGEAG GSEAREGAEQ LRAELLQERL RGQEQALRFE QERQTWQEEK ERVLRYQREI QGSYMDMYRR NQALEHELRL LREPPTSWSP RLESSKI Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
特异性
If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
产品特性
Key Benefits:
Predefined custom protein - from design to production - by highly experienced protein experts.
Protein expressed in mammalian cells and purified in one-step affinity chromatography
The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
State-of-the-art algorithm used for plasmid design (Gene synthesis).
This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
custom-made
N4BP3
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
N4BP3
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
限制
仅限研究用
状态
Liquid
缓冲液
The buffer composition is at the discretion of the manufacturer.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-80 °C
储存方法
Store at -80°C.
有效期
12 months
抗原
N4BP3
(NEDD4 Binding Protein 3 (N4BP3))
别名
N4bp3
背景
NEDD4-binding protein 3 (N4BP3),FUNCTION: Plays a positive role in the antiviral innate immune signaling pathway. Mechanistically, interacts with MAVS and functions as a positive regulator to promote 'Lys-63'-linked polyubiquitination of MAVS and thus strengthens the interaction between MAVS and TRAF2 (By similarity). Also plays a role in axon and dendrite arborization during cranial nerve development. May also be important for neural crest migration and early development of other anterior structures including eye, brain and cranial cartilage (By similarity). {ECO:0000250|UniProtKB:A0A1L8GXY6, ECO:0000250|UniProtKB:O15049}.