SLC25A47 Protein (AA 1-310) (His tag)
This Recombinant SLC25A47 protein is expressed in HEK-293 Cells.
产品编号 ABIN7557935
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for SLC25A47 Protein (AA 1-310) (His tag) (ABIN7557935)
抗原
See all SLC25A47 蛋白
SLC25A47
(Solute Carrier Family 25, Member 47 (SLC25A47))
蛋白类型
Recombinant
宿主
小鼠
资源
HEK-293 Cells
纯度
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
质量等级
custom-made
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产品特性
- AA 1-310
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标记
- This SLC25A47 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant Slc25a47 Protein expressed in mammalian cells.
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序列
- MDFVAGAIGG VCGVAVGYPL DTVKVRIQTE AKYAGIWHCI RDTYRQERVW GFYRGLSLPV CTVSLVSSVS FGTYHHCLAH ICRFRYGSTD AKPTKADITL SGCASGLVRV FLTSPTEVAK VRLQTQTQAQ TQQRRSSASW TSGAPALCPT PTACLEPRPK YSGPLHCLVT VAREEGLRGL YKGSSALLLR EGHSFATYFL SYAMLCEWLT PAGHSQPDVL GVLVAGGCAG VLAWAVATPM DVIKSRLQAD GQGQHRYRGL LHCVVTSVRE EGPRVLFKGL ALNCCRAFPV NMVVFVAYEA VLRLTQSLLT Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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Solute Carrier Family 25, Member 47 (SLC25A47) (AA 1-308) protein (His tag)
custom-made SLC25A47 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Solute Carrier Family 25, Member 47 (SLC25A47) (AA 1-308) protein (GST tag)SLC25A47 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- SLC25A47 (Solute Carrier Family 25, Member 47 (SLC25A47))
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别名
- Slc25a47
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背景
- Solute carrier family 25 member 47 (Hepatocellular carcinoma down-regulated mitochondrial carrier homolog) (Mitochondrial NAD(+) transporter SLC25A47),FUNCTION: Mitochondrial NAD(+) transporter that acts as a 'metabolic gate' in hepatic lipogenesis. Provides NAD(+) substrate to mitochondrial SIRT3 deacetylase and enables its NAD(+)-dependent activities in mitochondrial energy metabolism. This triggers downstream activation of PRKAA1/AMPK-alpha signaling cascade that negatively regulates sterol regulatory element-binding protein (SREBP) transcriptional activities and ATP-consuming lipogenesis to restore cellular energy balance. May transport other mitochondrial metabolites having an aromatic nucleotide and phosphate groups, such as acetyl-CoA. Does not transport amino acids. The transport mechanism remains to be elucidated. {ECO:0000269|PubMed:36804859}.
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分子量
- 33.6 kDa
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UniProt
- Q6IS41
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AlphaFold
- Q6IS41
抗原
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