SDHAF1 Protein (AA 1-118) (His tag)
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北京 101111
Quick Overview for SDHAF1 Protein (AA 1-118) (His tag) (ABIN7557132)
抗原
See all SDHAF1 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-118
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标记
- This SDHAF1 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant Sdhaf1 Protein expressed in mammalian cells.
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序列
- MSRPSRLQRQ VLSLYRELLR AGRGTPGAEA RVRAEFRQHA SLPRTDVLRI EYLYRRGRRQ LQLLRSGHAT AMGTFVRPRG PAEEPGDATA PGTRLDDGGA PKNSCEDTGA RETRSDGR Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- SDHAF1 (Succinate Dehydrogenase Complex Assembly Factor 1 (SDHAF1))
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别名
- Sdhaf1
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背景
- Succinate dehydrogenase assembly factor 1, mitochondrial (SDH assembly factor 1) (SDHAF1) (LYR motif-containing protein 8),FUNCTION: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit Sdhb of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF3. Contributes to iron-sulfur cluster incorporation into SDHB by binding to SDHB and recruiting the iron-sulfur transfer complex formed by HSC20, HSPA9 and ISCU through direct binding to HSC20. {ECO:0000250|UniProtKB:A6NFY7}.
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分子量
- 13.1 kDa
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UniProt
- Q3U276
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AlphaFold
- Q3U276
抗原
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