PRRX1 Protein (AA 1-245) (His tag)
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北京 101111
Quick Overview for PRRX1 Protein (AA 1-245) (His tag) (ABIN7556634)
抗原
See all PRRX1 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-245
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标记
- This PRRX1 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant Prrx1 Protein expressed in mammalian cells.
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序列
- MTSSYGHVLE RQPALGGRLD SPGNLDTLQA KKNFSVSHLL DLEEAGDMVA AQADESVGEA GRSLLESPGL TSGSDTPQQD NDQLNSEEKK KRKQRRNRTT FNSSQLQALE RVFERTHYPD AFVREDLARR VNLTEARVQV WFQNRRAKFR RNERAMLANK NASLLKSYSG DVTAVEQPIV PRPAPRPTDY LSWGTASPYS AMATYSATCA NNSPAQGINM ANSIANLRLK AKEYSLQRNQ VPTVN Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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Paired Related Homeobox 1 (PRRX1) (AA 1-245) protein (His tag)
custom-made PRRX1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Paired Related Homeobox 1 (PRRX1) (AA 1-217) protein (His-IF2DI Tag)PRRX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Paired Related Homeobox 1 (PRRX1) (AA 1-217) protein (GST tag)PRRX1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Paired Related Homeobox 1 (PRRX1) (AA 1-217) protein (His tag)PRRX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
Paired Related Homeobox 1 (PRRX1) protein (Myc-DYKDDDDK Tag)PRRX1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- PRRX1 (Paired Related Homeobox 1 (PRRX1))
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别名
- Prrx1
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背景
- Paired mesoderm homeobox protein 1 (Homeobox protein K-2) (Muscle homeobox protein) (MHox) (Paired-related homeobox protein 1) (PRX-1),FUNCTION: Master transcription factor of stromal fibroblasts for myofibroblastic lineage progression. Orchestrates the functional drift of fibroblasts into myofibroblastic phenotype via TGF-beta signaling by remodeling a super-enhancer landscape. Through this function, plays an essential role in wound healing process (PubMed:35589735). Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer (PubMed:1360403). May play a role in homeostasis and regeneration of bone, white adipose tissue and derm (PubMed:36456880). {ECO:0000269|PubMed:1360403, ECO:0000269|PubMed:35589735, ECO:0000269|PubMed:36456880}., FUNCTION: [Isoform 1]: Transcriptional activator, when transfected in fibroblastic or myoblastic cell lines. This activity may be masked by the C-terminal OAR domain. {ECO:0000269|PubMed:11373278}., FUNCTION: [Isoform 2]: Transcriptional repressor, when transfected in fibroblastic or myoblastic cell lines. {ECO:0000269|PubMed:11373278}.
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分子量
- 27.3 kDa
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UniProt
- P63013
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AlphaFold
- P63013
抗原
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