ARIH2 Protein (AA 1-492) (His tag)
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北京 101111
Quick Overview for ARIH2 Protein (AA 1-492) (His tag) (ABIN7556384)
抗原
See all ARIH2 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-492
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标记
- This ARIH2 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant Arih2 Protein expressed in mammalian cells.
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序列
- MSVDMNSQGS DSNEEDYDPN CEEEEEEEED PGDIEDYYVG VASDVEQQGA DAFDPEEYQF TCLTYKESEG ALHEHMTSLA SVLKVSHSVA KLILVNFHWQ VSEILDRYRS NSAQLLVEAR VQPNPSKHVP TAHPPHHCAV CMQFVRKENL LSLACQHQFC RSCWEQHCSV LVKDGVGVGI SCMAQDCPLR TPEDFVFPLL PNEELRDKYR RYLFRDYVES HFQLQLCPGA DCPMVIRVQE PRARRVQCNR CSEVFCFKCR QMYHAPTDCA TIRKWLTKCA DDSETANYIS AHTKDCPKCN ICIEKNGGCN HMQCSKCKHD FCWMCLGDWK THGSEYYECS RYKENPDIVN QSQQAQAREA LKKYLFYFER WENHNKSLQL EAQTYERIHE KIQERVMNNL GTWIDWQYLQ NAAKLLAKCR YTLQYTYPYA YYMESGPRKK LFEYQQAQLE AEIENLSWKV ERADSYDRGD LENQMHIAEQ RRRTLLKDFH DT Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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protein ariadne-2 homolog (ARIH2) (AA 1-493) protein (His tag)
custom-made ARIH2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
protein ariadne-2 homolog (ARIH2) (AA 1-493) protein (GST tag)ARIH2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
protein ariadne-2 homolog (ARIH2) protein (Myc-DYKDDDDK Tag)ARIH2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- ARIH2 (protein ariadne-2 homolog (ARIH2))
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别名
- Arih2
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背景
- E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein) (UbcM4-interacting protein 48),FUNCTION: E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (By similarity). Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets (By similarity). The initial ubiquitin is then elongated (By similarity). E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex. Mediates 'Lys-6', 'Lys-48'- and 'Lys-63'-linked polyubiquitination. May play a role in myelopoiesis (By similarity). {ECO:0000250|UniProtKB:O95376, ECO:0000250|UniProtKB:Q9Y4X5}.
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分子量
- 57.7 kDa
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UniProt
- Q9Z1K6
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AlphaFold
- Q9Z1K6
抗原
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