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PTPLAD1 Protein (AA 1-362) (His tag)

This Recombinant PTPLAD1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7554074
发货至: 中国
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Quick Overview for PTPLAD1 Protein (AA 1-362) (His tag) (7554074)

抗原

See all PTPLAD1 蛋白
PTPLAD1 (Protein tyrosine Phosphatase-Like A Domain Containing 1 (PTPLAD1))

蛋白类型

Recombinant

宿主

  • 2
  • 2

资源

  • 2
  • 1
  • 1
HEK-293 Cells

纯度

> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

质量等级

custom-made
  • 产品特性

    AA 1-362

    标记

    This PTPLAD1 protein is labelled with His tag.

    原理

    Predefined custom protein recombinant HACD3 Protein expressed in mammalian cells.

    序列

    MENQVLTPHV YWAQRHRELY LRVELSDVQN PAISITENVL HFKAQGHGAK GDNVYEFHLE FLDLVKPEPV YKLTQRQVNI TVQKKVSQWW ERLTKQEKRP LFLAPDFDRW LDESDAEMEL RAKEEERLNK LRLESEGSPE TLTNLRKGYL FMYNLVQFLG FSWIFVNLTV RFCILGKESF YDTFHTVADM MYFCQMLAVV ETINAAIGVT TSPVLPSLIQ LLGRNFILFI IFGTMEEMQN KAVVFFVFYL WSAIEIFRYS FYMLTCIDMD WKVLTWLRYT LWIPLYPLGC LAEAVSVIQS IPIFNETGRF SFTLPYPVKI KVRFSFFLQI YLIMIFLGLY INFRHLYKQR RRRYGQKKKK IH Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

    特异性

    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

    产品特性

    Key Benefits:
    • Predefined custom protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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    Product
    表达系统
    Conjugate
    Origin
    Price
    表达系统 Wheat germ
    Conjugate GST tag
    Origin Human
    Price 7,620.69 ¥

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  • 应用备注

    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The buffer composition is at the discretion of the manufacturer.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -80 °C

    储存方法

    Store at -80°C.

    有效期

    12 months
  • 抗原

    PTPLAD1 (Protein tyrosine Phosphatase-Like A Domain Containing 1 (PTPLAD1))

    别名

    HACD3

    背景

    Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (hB-ind1) (Protein-tyrosine phosphatase-like A domain-containing protein 1),FUNCTION: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May be involved in Rac1-signaling pathways leading to the modulation of gene expression. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (PubMed:25687571). {ECO:0000269|PubMed:10747961, ECO:0000269|PubMed:18554506, ECO:0000269|PubMed:25687571}.

    分子量

    43.2 kDa

    UniProt

    Q9P035

    AlphaFold

    Q9P035
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