YWHAB Protein (AA 1-246) (His tag)
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- 抗原 See all YWHAB 蛋白
- YWHAB (14-3-3 alpha + beta (YWHAB))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-246
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This YWHAB protein is labelled with His tag.
- 原理
- Custom-made recombinant YWHAB Protein expressed in mammalian cells.
- 序列
- MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL ELLDKYLIPN ATQPESKVFY LKMKGDYFRY LSEVASGDNK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD AGEGEN Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product YWHAB 蛋白
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14-3-3 alpha + beta (YWHAB) (AA 1-246) protein (His tag)
custom-made YWHAB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
14-3-3 alpha + beta (YWHAB) (AA 1-246) protein (His tag)YWHAB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
14-3-3 alpha + beta (YWHAB) (AA 1-246) protein (GST tag)YWHAB 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
14-3-3 alpha + beta (YWHAB) (AA 1-246) proteinYWHAB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
14-3-3 alpha + beta (YWHAB) (AA 1-246), (full length) protein (GST tag)YWHAB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 95 % ELISA
14-3-3 alpha + beta (YWHAB) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)YWHAB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
14-3-3 alpha + beta (YWHAB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)YWHAB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- YWHAB (14-3-3 alpha + beta (YWHAB))
- 别名
- YWHAB (YWHAB 产品)
- 背景
- 14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed],FUNCTION: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13. {ECO:0000269|PubMed:17717073, ECO:0000269|PubMed:19592491, ECO:0000269|PubMed:21224381}.
- 分子量
- 28.1 kDa
- UniProt
- P31946
- AlphaFold
- P31946
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location
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