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HOMER3 Protein (AA 1-361) (His tag)

This Recombinant HOMER3 protein is expressed in HEK-293 Cells.
产品编号 ABIN7548337
发货至: 中国

Quick Overview for HOMER3 Protein (AA 1-361) (His tag) (ABIN7548337)

抗原

See all HOMER3 蛋白
HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))

蛋白类型

Recombinant

宿主

  • 7
  • 2

资源

  • 4
  • 2
  • 2
  • 1
HEK-293 Cells

纯度

> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

质量等级

custom-made
  • 产品特性

    AA 1-361

    标记

    This HOMER3 protein is labelled with His tag.

    原理

    Predefined custom protein recombinant HOMER3 Protein expressed in mammalian cells.

    序列

    MSTAREQPIF STRAHVFQID PATKRNWIPA GKHALTVSYF YDATRNVYRI ISIGGAKAII NSTVTPNMTF TKTSQKFGQW ADSRANTVYG LGFASEQHLT QFAEKFQEVK EAARLAREKS QDGGELTSPA LGLASHQVPP SPLVSANGPG EEKLFRSQSA DAPGPTERER LKKMLSEGSV GEVQWEAEFF ALQDSNNKLA GALREANAAA AQWRQQLEAQ RAEAERLRQR VAELEAQAAS EVTPTGEKEG LGQGQSLEQL EALVQTKDQE IQTLKSQTGG PREALEAAER EETQQKVQDL ETRNAELEHQ LRAMERSLEE ARAERERARA EVGRAAQLLD VSLFELSELR EGLARLAEAA P Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

    特异性

    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

    产品特性

    Key Benefits:
    • Predefined custom protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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    Conjugate
    Origin
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    表达系统 Escherichia coli (E. coli)
    Conjugate
    Origin Human
    Price 20,381.36 ¥
    表达系统 HEK-293 Cells
    Conjugate Myc-DYKDDDDK Tag
    Origin Human
    Price 10,775.98 ¥
    表达系统 HEK-293 Cells
    Conjugate Myc-DYKDDDDK Tag
    Origin Human
    Price 10,775.98 ¥
    表达系统 HEK-293 Cells
    Conjugate Myc-DYKDDDDK Tag
    Origin Human
    Price 10,775.98 ¥

    您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案

  • 应用备注

    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The buffer composition is at the discretion of the manufacturer.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -80 °C

    储存方法

    Store at -80°C.

    有效期

    12 months
  • 抗原

    HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))

    别名

    HOMER3

    背景

    Homer protein homolog 3 (Homer-3),FUNCTION: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (PubMed:18218901). {ECO:0000269|PubMed:18218901}.

    分子量

    39.8 kDa

    UniProt

    Q9NSC5

    AlphaFold

    Q9NSC5
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