CYP3A7 Protein (AA 1-503) (His tag)
This Recombinant CYP3A7 protein is expressed in HEK-293 Cells.
产品编号 ABIN7546791
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for CYP3A7 Protein (AA 1-503) (His tag) (ABIN7546791)
抗原
See all CYP3A7 蛋白
CYP3A7
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7))
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
纯度
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
质量等级
custom-made
-
-
产品特性
- AA 1-503
-
标记
- This CYP3A7 protein is labelled with His tag.
-
原理
- Predefined custom protein recombinant CYP3A7 Protein expressed in mammalian cells.
-
序列
- MDLIPNLAVE TWLLLAVSLI LLYLYGTRTH GLFKKLGIPG PTPLPFLGNA LSFRKGYWTF DMECYKKYRK VWGIYDCQQP MLAITDPDMI KTVLVKECYS VFTNRRPFGP VGFMKNAISI AEDEEWKRIR SLLSPTFTSG KLKEMVPIIA QYGDVLVRNL RREAETGKPV TLKHVFGAYS MDVITSTSFG VSIDSLNNPQ DPFVENTKKL LRFNPLDPFV LSIKVFPFLT PILEALNITV FPRKVISFLT KSVKQIKEGR LKETQKHRVD FLQLMIDSQN SKDSETHKAL SDLELMAQSI IFIFAGYETT SSVLSFIIYE LATHPDVQQK VQKEIDTVLP NKAPPTYDTV LQLEYLDMVV NETLRLFPVA MRLERVCKKD VEINGMFIPK GVVVMIPSYV LHHDPKYWTE PEKFLPERFS KKNKDNIDPY IYTPFGSGPR NCIGMRFALV NMKLALVRVL QNFSFKPCKE TQIPLKLRFG GLLLTEKPIV LKAESRDETV SGA Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
-
特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
-
产品特性
-
Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
-
-
想要此Protein的其他选项吗？
!探索我们的目录蛋白和定制蛋白服务选项！Product表达系统ConjugateOriginPrice表达系统 Wheat germConjugate GST tagOrigin HumanPrice 5,782.24 ¥表达系统 Escherichia coli (E. coli)Conjugate His tagOrigin HumanPrice 7,783.78 ¥表达系统 BacteriaConjugate His tagOrigin HumanPrice 3,968.25 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
-
Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7) (AA 1-503) protein (GST tag)
CYP3A7 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
-
-
应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The buffer composition is at the discretion of the manufacturer.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -80 °C
-
储存方法
- Store at -80°C.
-
有效期
- 12 months
-
-
- CYP3A7 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7))
-
别名
- CYP3A7
-
背景
- Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (Cytochrome P450-HFLA) (P450HLp2),FUNCTION: A cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins during embryogenesis (PubMed:9555064, PubMed:11093772, PubMed:14559847, PubMed:12865317, PubMed:17178770). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:9555064, PubMed:11093772, PubMed:14559847, PubMed:12865317, PubMed:17178770). Catalyzes the hydroxylation of carbon-hydrogen bonds. Metabolizes 3beta-hydroxyandrost-5-en-17-one (dehydroepiandrosterone, DHEA), a precursor in the biosynthesis of androgen and estrogen steroid hormones (PubMed:9555064, PubMed:17178770). Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1), particularly D-ring hydroxylated estrone at the C16-alpha position (PubMed:14559847, PubMed:12865317). Mainly hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may play a role in atRA clearance during fetal development (PubMed:11093772). Also involved in the oxidative metabolism of xenobiotics including anticonvulsants (PubMed:9555064). {ECO:0000269|PubMed:11093772, ECO:0000269|PubMed:12865317, ECO:0000269|PubMed:14559847, ECO:0000269|PubMed:17178770, ECO:0000269|PubMed:9555064}.
-
分子量
- 57.5 kDa
-
UniProt
- P24462
-
AlphaFold
- P24462
-
途径
- Steroid Hormone Biosynthesis
抗原
-
You are here:
