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P2RY2 蛋白

This Synthetic Nanodisc P2RY2 protein is expressed in Mammalian Cells.
产品编号 ABIN7538499
发货至: 中国

Quick Overview for P2RY2 蛋白 (ABIN7538499)

抗原

See all P2RY2 蛋白
P2RY2 (Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2))

蛋白类型

Synthetic Nanodisc

宿主

  • 7
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资源

  • 3
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Mammalian Cells
  • 原理

    Human P2RY2 full length protein-synthetic nanodisc

    产品特性

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    表达系统
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    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    P2RY2 (Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2))

    别名

    P2RY2

    背景

    The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]

    分子量

    The human full length P2RY2 protein has a MW of 42.3kDa

    UniProt

    P41231

    途径

    Cellular Response to Molecule of Bacterial Origin, Smooth Muscle Cell Migration
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