PTH2R 蛋白
This Synthetic Nanodisc PTH2R protein is expressed in Mammalian Cells.
Quick Overview for PTH2R 蛋白 (ABIN7538469)
抗原
See all PTH2R 蛋白
PTH2R
(Parathyroid Hormone 2 Receptor (PTH2R))
蛋白类型
Synthetic Nanodisc
宿主
人
资源
Mammalian Cells
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原理
- Human PTH2R full length protein-synthetic nanodisc
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产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Parathyroid Hormone 2 Receptor (PTH2R) (AA 27-145), (Extracellular) protein (His-SUMO Tag)
PTH2R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- PTH2R (Parathyroid Hormone 2 Receptor (PTH2R))
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别名
- PTH2R
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背景
- The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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分子量
- The human full length PTH2R protein has a MW of 62.2kDa
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UniProt
- P49190
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途径
- cAMP Metabolic Process
抗原
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