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OPN1SW 蛋白

This Synthetic Nanodisc OPN1SW protein is expressed in Mammalian Cells.
产品编号 ABIN7538458
发货至: 中国

Quick Overview for OPN1SW 蛋白 (ABIN7538458)

抗原

See all OPN1SW 蛋白
OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

蛋白类型

Synthetic Nanodisc

宿主

  • 2
  • 2

资源

  • 2
  • 1
  • 1
Mammalian Cells
  • 原理

    Human OPSB full length protein-synthetic nanodisc

    产品特性

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

    别名

    OPSB

    背景

    This gene belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. [provided by RefSeq, Jul 2008]

    分子量

    The human full length OPSB protein has a MW of 38.7kDa

    UniProt

    P03999
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