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NPY5R 蛋白

This Synthetic Nanodisc NPY5R protein is expressed in Mammalian Cells.
产品编号 ABIN7538410
发货至: 中国

Quick Overview for NPY5R 蛋白 (ABIN7538410)

抗原

See all NPY5R 蛋白
NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

蛋白类型

Synthetic Nanodisc

宿主

  • 7
  • 4
  • 2

资源

  • 6
  • 3
  • 2
  • 2
Mammalian Cells
  • 原理

    Human NPY5R full length protein-synthetic nanodisc

    产品特性

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    表达系统
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    Origin
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    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
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    价格从 172,528.32 ¥

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  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

    别名

    NPY5R

    背景

    The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015]

    分子量

    The human full length NPY5R protein has a MW of 50.7kDa

    UniProt

    Q15761

    途径

    Feeding Behaviour
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