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NPY2R 蛋白

This Synthetic Nanodisc NPY2R protein is expressed in Mammalian Cells.
产品编号 ABIN7538409
发货至: 中国

Quick Overview for NPY2R 蛋白 (ABIN7538409)

抗原

See all NPY2R 蛋白
NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))

蛋白类型

Synthetic Nanodisc

宿主

  • 7
  • 4
  • 2

资源

  • 6
  • 3
  • 2
  • 2
Mammalian Cells
  • 原理

    Human NPY2R full length protein-synthetic nanodisc

    产品特性

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    NPY2R (Neuropeptide Y Receptor Y2 (NPY2R))

    别名

    NPY2R

    背景

    Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.[UniProtKB/Swiss-Prot Function]

    分子量

    The human full length NPY2R protein has a MW of 42.7kDa

    UniProt

    P49146

    途径

    cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour
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