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Leukotriene B4 Receptor/BLT 蛋白

This Synthetic Nanodisc Leukotriene B4 Receptor/BLT protein is expressed in Mammalian Cells.
产品编号 ABIN7538357
发货至: 中国

Quick Overview for Leukotriene B4 Receptor/BLT 蛋白 (ABIN7538357)

抗原

See all Leukotriene B4 Receptor/BLT (LTB4R) 蛋白
Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

蛋白类型

Synthetic Nanodisc

宿主

  • 4
  • 2

资源

  • 3
  • 2
  • 1
Mammalian Cells
  • 原理

    Human LT4R1 full length protein-synthetic nanodisc

    产品特性

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    表达系统
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    Origin
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    表达系统 HEK-293 Cells
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    Origin Human
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    Origin Human
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  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

    别名

    LT4R1

    背景

    Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.[UniProtKB/Swiss-Prot Function]

    分子量

    The human full length LT4R1 protein has a MW of 37.6kDa

    UniProt

    Q15722
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