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GPR34 蛋白

This Synthetic Nanodisc GPR34 protein is expressed in Mammalian Cells.
产品编号 ABIN7538271
发货至: 中国

Quick Overview for GPR34 蛋白 (ABIN7538271)

抗原

See all GPR34 蛋白
GPR34 (G Protein-Coupled Receptor 34 (GPR34))

蛋白类型

Synthetic Nanodisc

宿主

  • 5
  • 2

资源

  • 3
  • 2
  • 2
Mammalian Cells
  • 原理

    Human GPR34 full length protein-synthetic nanodisc

    产品特性

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    表达系统
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    表达系统 HEK-293 Cells
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    Origin Human
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    Origin Human
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  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    GPR34 (G Protein-Coupled Receptor 34 (GPR34))

    别名

    GPR34

    背景

    G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM, Apr 2006]

    分子量

    The human full length GPR34 protein has a MW of 43.9kDa

    UniProt

    Q9UPC5
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