Calcitonin Receptor Protein (CALCR)
This Synthetic Nanodisc Calcitonin Receptor protein is expressed in Mammalian Cells.
Quick Overview for Calcitonin Receptor Protein (CALCR) (ABIN7538150)
抗原
See all Calcitonin Receptor (CALCR) 蛋白
Calcitonin Receptor (CALCR)
蛋白类型
Synthetic Nanodisc
宿主
人
资源
Mammalian Cells
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原理
- Human CALCR full length protein-synthetic nanodisc
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产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Calcitonin Receptor (CALCR) (AA 1-474) protein (GST tag)
CALCR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- Calcitonin Receptor (CALCR)
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别名
- CALCR
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背景
- This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
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分子量
- The human full length CALCR protein has a MW of 55.3kDa
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UniProt
- P30988
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途径
- cAMP Metabolic Process
抗原
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