ADRB3 蛋白
Quick Overview for ADRB3 蛋白 (ABIN7538128)
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See all ADRB3 蛋白蛋白类型
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资源
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                                            原理
- Human ADRB3 full length protein-synthetic nanodisc
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                                            产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
 
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                                            说明
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                        Advantages of Synthetic Nanodiscs: - Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
 - Intolerant to acids and high concentrations of divalent metal ions
 
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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                                            有效期
- 12 months
 
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    - ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
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                                            别名
- ADRB3
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                                            背景
- The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]
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                                            分子量
- The human full length ADRB3 protein has a MW of 43.5kDa
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                                            UniProt
- P13945
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                                            途径
- cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation
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