PDGF-BB Homodimer (Active) 蛋白
Quick Overview for PDGF-BB Homodimer (Active) 蛋白 (ABIN7520387)
抗原
蛋白类型
生物活性
宿主
资源
-
-
原理
- Recombinant Human PDGF-BB Protein
-
序列
- SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TVAAARPVT
-
特异性
- Ser82-Thr190
-
过滤
- 0.22 μm filtered
-
内毒素水平
- < 0.1EU/μg
-
Biological Activity Comment
- Measured by its binding ability in a functional ELISA.Immobilized PDGF-BB at 2 μg/mL (100 μL/well) can bind Human PDGFRB with a linear range of 0.1-104.7 ng/mL.
-
-
PDGF-BB Homodimer (Active) protein (His tag)
宿主: 人 宿主: 酵母菌 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
PDGF-BB Homodimer protein宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 98 % as determined by reducing SDS-PAGE.
PDGF-BB Homodimer (AA 82-190) (Active) protein宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by reducing (R) and non-reducing (NR) SDS-PAGE. Active
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
-
浓度
- 0.3 mg/mL
-
缓冲液
- Lyophilized from a 0.22 μm filtered solution of 20 mM NaAc, pH 4.5.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
-
-
- PDGF-BB Homodimer
-
别名
- PDGF-BB
-
背景
-
Description: Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.
Name: SIS, SSV, IBGC5, PDGF2, c-sis, PDGF-2,PDGF subunit B,PDGF-BB,PDGFB
-
基因ID
- 5155
-
UniProt
- P01127
抗原
-
