P-Cadherin Protein (CDH3) (His tag)
Quick Overview for P-Cadherin Protein (CDH3) (His tag) (ABIN7520380)
抗原
See all P-Cadherin (CDH3) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This P-Cadherin protein is labelled with His tag.
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原理
- Active Recombinant Human CDH3/P-cadherin Protein
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序列
- DWVVAPISVP ENGKGPFPQR LNQLKSNKDR DTKIFYSITG PGADSPPEGV FAVEKETGWL LLNKPLDREE IAKYELFGHA VSENGASVED PMNISIIVTD QNDHKPKFTQ DTFRGSVLEG VLPGTSVMQV TATDEDDAIY TYNGVVAYSI HSQEPKDPHD LMFTIHRSTG TISVISSGLD REKVPEYTLT IQATDMDGDG STTTAVAVVE ILDANDNAPM FDPQKYEAHV PENAVGHEVQ RLTVTDLDAP NSPAWRATYL IMGGDDGDHF TITTHPESNQ GILTTRKGLD FEAKNQHTLY VEVTNEAPFV LKLPTSTATI VVHVEDVNEA PVFVPPSKVV EVQEGIPTGE PVCVYTAEDP DKENQKISYR ILRDPAGWLA MDPDSGQVTA VGTLDREDEQ FVRNNIYEVM VLAMDNGSPP TTGTGTLLLT LIDVNDHGPV PEPRQITICN QSPVRQVLNI TDKDLSPHTS PFQAQLTDDS DIYWTAEVNE EGDTVVLSLK KFLKQDTYDV HLSLSDHGNK EQLTVIRATV CDCHGHVETC PGPWKGG
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特异性
- Asp108-Gly654
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过滤
- 0.22 μm filtered
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内毒素水平
- <1EU/μg
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Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of A431 human epithelial carcinoma cells. When 1x105 cells/well are added to rhP-CAD/Fc Chimera coated plates (10 μg/mL with 100 μL/well), approximately 50-60% will adhere after 1.5 hours at 37° C.
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P-Cadherin (CDH3) (AA 108-654) protein (His tag)
CDH3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
P-Cadherin (CDH3) (AA 100-647) protein (His tag)CDH3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
P-Cadherin (CDH3) (AA 1-829) protein (GST tag)CDH3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
P-Cadherin (CDH3) protein (Fc Tag)CDH3 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by SDS-PAGE
P-Cadherin (CDH3) (AA 108-654) protein (His tag)CDH3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
P-Cadherin (CDH3) (AA 18-654) protein (His tag)CDH3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
P-Cadherin (CDH3) protein (Myc-DYKDDDDK Tag)CDH3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- P-Cadherin (CDH3)
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别名
- CDH3/P-cadherin
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背景
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Description: Cadherin-3 (also known as P-cadherin)is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. In humans, cadherin-3 is only detected in a few organs. However, its overexpression is strongly associated with a poor prognosis in some solid tumors including breast, lung and pancreatic cancers.
Name: CDH3,CDHP,HJMD,PCAD
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基因ID
- 1001
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UniProt
- P22223
抗原
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