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Nectin-2 Protein (NECTIN2) (His tag)

This Recombinant Nectin-2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7535985
发货至: 中国

Quick Overview for Nectin-2 Protein (NECTIN2) (His tag) (ABIN7535985)

抗原

Nectin-2 (NECTIN2)

蛋白类型

Recombinant

宿主

小鼠

资源

  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

> 95 % by SDS-PAGE.
  • 标记

    This Nectin-2 protein is labelled with His tag.

    原理

    Recombinant Mouse Nectin-2/PVRL2/CD112 Protein

    序列

    QDVRVRVLPE VRGRLGGTVE LPCHLLPPTT ERVSQVTWQR LDGTVVAAFH PSFGVDFPNS QFSKDRLSFV RARPETNADL RDATLAFRGL RVEDEGNYTC EFATFPNGTR RGVTWLRVIA QPENHAEAQE VTIGPQSVAV ARCVSTGGRP PARITWISSL GGEAKDTQEP GIQAGTVTII SRYSLVPVGR ADGVKVTCRV EHESFEEPIL LPVTLSVRYP PEVSISGYDD NWYLGRSEAI LTCDVRSNPE PTDYDWSTTS GVFPASAVAQ GSQLLVHSVD RMVNTTFICT ATNAVGTGRA EQVILVRESP STAGAGATGG

    特异性

    Gln32-Gly351

    过滤

    0.22 μm filtered

    内毒素水平

    <0.1EU/μg
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    缓冲液

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原

    Nectin-2 (NECTIN2)

    别名

    Nectin-2/PVRL2/CD112

    背景

    Description: Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+?T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.

    Name: CD112,Nectin-2,PVRL2,PVRL2

    基因ID

    19294

    UniProt

    P32507-1
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