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IL-11 蛋白

IL11 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % by SDS-PAGE. Active
产品编号 ABIN7533816
发货至: 中国
  • 抗原 See all IL-11 (IL11) 蛋白
    IL-11 (IL11) (Interleukin 11 (IL11))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 17
    • 11
    • 2
    • 2
    资源
    • 12
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Active Recombinant Human IL-11 Protein
    序列
    PGPPPGPPRV SPDPRAELDS TVLLTRSLLA DTRQLAAQLR DKFPADGDHN LDSLPTLAMS AGALGALQLP GVLTRLRADL LSYLRHVQWL RRAGGSSLKT LEPELGTLQA RLDRLLRRLQ LLMSRLALPQ PPPDPPAPPL APPSSAWGGI RAAHAILGGL HLTLDWAVRG LLLLKTRL
    特异性
    Pro22-Leu199
    纯度
    > 97 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 1.0 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 1.3-5 ng/mL, corresponding to a specific activity of 2x105-7.69x105units/mg.
    Top Product
    Discover our top product IL11 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    IL-11 (IL11) (Interleukin 11 (IL11))
    别名
    IL-11 (IL11 产品)
    别名
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    背景

    Description: The protein is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.

    Name: IL11,AGIF,IL-11

    基因ID
    3589
    UniProt
    P20809
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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