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FABP4 Protein (Ala29Thr)

This Recombinant FABP4 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7533802
发货至: 中国

Quick Overview for FABP4 Protein (Ala29Thr) (ABIN7533802)

抗原

See all FABP4 蛋白
FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

蛋白类型

Recombinant

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE.
  • 产品特性

    Ala29Thr

    原理

    Recombinant Human FABP4/A-FABP/ALBP(A29T) Protein

    序列

    CDAFVGTWKL VSSENFDDYM KEVGVGFTTR KVAGMAKPNM IISVNGDVIT IKSESTFKNT EISFILGQEF DEVTADDRKV KSTITLDGGV LVHVQKWDGK STTIKRKRED DKLVVECVMK GVTSTRVYER A

    特异性

    Cys2-Ala132(A29T)

    过滤

    0.22 μm filtered

    内毒素水平

    < 1.0 EU/μg of the protein by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    缓冲液

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原

    FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

    别名

    FABP4/A-FABP/ALBP

    背景

    Description: Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein. It is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.

    Name: A-FABP, AFABP, ALBP, HEL-S-104, aP2,FABP4,AFABP,ALBP,HEL-S-104,aP2

    基因ID

    2167

    UniProt

    P15090

    途径

    Brown Fat Cell Differentiation
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