FABP4 Protein (Ala29Thr)
Quick Overview for FABP4 Protein (Ala29Thr) (ABIN7533802)
抗原
See all FABP4 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- Ala29Thr
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原理
- Recombinant Human FABP4/A-FABP/ALBP(A29T) Protein
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序列
- CDAFVGTWKL VSSENFDDYM KEVGVGFTTR KVAGMAKPNM IISVNGDVIT IKSESTFKNT EISFILGQEF DEVTADDRKV KSTITLDGGV LVHVQKWDGK STTIKRKRED DKLVVECVMK GVTSTRVYER A
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特异性
- Cys2-Ala132(A29T)
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过滤
- 0.22 μm filtered
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内毒素水平
- < 1.0 EU/μg of the protein by LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C,-80 °C
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储存方法
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))
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别名
- FABP4/A-FABP/ALBP
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背景
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Description: Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein. It is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.
Name: A-FABP, AFABP, ALBP, HEL-S-104, aP2,FABP4,AFABP,ALBP,HEL-S-104,aP2
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基因ID
- 2167
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UniProt
- P15090
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途径
- Brown Fat Cell Differentiation
抗原
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