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EPO 蛋白

This Recombinant EPO protein is expressed in HEK-293 Cells.

产品编号 ABIN7519966

发货至: 中国

Quick Overview for EPO 蛋白 (ABIN7519966)

抗原

See all EPO 蛋白

EPO (Erythropoietin (EPO))

蛋白类型

Recombinant

生物活性

Active

宿主

19
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4
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3
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2
2
1
1
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1

人

资源

19
15
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1
1

HEK-293 Cells

纯度

> 92 % by SDS-PAGE.

Discover our top product EPO 蛋白

原理

Active Recombinant Human Erythropoietin/EPO Protein

序列

APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGDR

特异性

Ala28-Arg193

过滤

0.22 μm filtered

内毒素水平

<0.1EU/μg

Biological Activity Comment

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED₅₀ for this effect is 0.07-0.27 ng/mL, corresponding to a specific activity of 3.70 x 10⁶~1.43x 10⁷ units/mg.
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Erythropoietin (EPO) (AA 28-193) (Active) protein
EPO 宿主: 人宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active

Erythropoietin (EPO) (Active) protein (His tag)
EPO 宿主: 小鼠宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active

Erythropoietin (EPO) (AA 1-193) protein (GST tag)
EPO 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Erythropoietin (EPO) (AA 28-193) protein (His tag)
EPO 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by reducing SDS-PAGE.

Erythropoietin (EPO) (AA 28-193) protein
EPO 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Erythropoietin (EPO) protein (His tag)
EPO 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, ELISA

Erythropoietin (EPO) protein (His tag)
EPO 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, ELISA

Erythropoietin (EPO) (Active) protein (His tag)
EPO 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active

Erythropoietin (EPO) (AA 27-192) (Active) protein (His tag)
EPO 宿主: 小鼠宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active

Erythropoietin (EPO) (AA 82-192) protein (His tag,GST tag)
EPO 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS, WB, Imm, PC

限制

仅限研究用
状态

Lyophilized

溶解方式

Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

缓冲液

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

储存条件

-20 °C,-80 °C

储存方法

Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
抗原

EPO (Erythropoietin (EPO))

别名

Erythropoietin/EPO

物质类

Hormone

背景

Description: Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type a... single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
Name: EP, DBAL, ECYT5, MVCD2,EPO,Erythropoietin

基因ID

2056

UniProt

P01588

途径

JAK/STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity

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