beta-2 Microglobulin Protein (His tag)
Quick Overview for beta-2 Microglobulin Protein (His tag) (ABIN7533951)
抗原
See all beta-2 Microglobulin (B2M) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This beta-2 Microglobulin protein is labelled with His tag.
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原理
- Active Recombinant Human Beta-2-microglobulin/B2M Protein
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序列
- IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM
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特异性
- Ile21-Met119
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过滤
- 0.22 μm filtered
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内毒素水平
- < 0.1 EU/μg of the protein by LAL method.
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Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human B2M at 2 μg/mL (100 μL/well) can bind Recombinant Human CD8 alpha with a linear range of 31.25-341 ng/mL.
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beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)
B2M 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)B2M 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 21-119) protein (Fc Tag)B2M 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 21-119) protein (Fc Tag)B2M 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 1-119) protein (GST tag)B2M 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C,-80 °C
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储存方法
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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别名
- Beta-2-microglobulin/B2M
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背景
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Description: This protein is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Name: B2M, IMD43, beta-2-microglobulin,IMD43
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基因ID
- 567
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UniProt
- P61769
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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