DKK3 Protein (AA 1-349) (His tag)
Quick Overview for DKK3 Protein (AA 1-349) (His tag) (ABIN7505749)
抗原
蛋白类型
宿主
资源
纯度
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产品特性
- AA 1-349
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标记
- This DKK3 protein is labelled with His tag.
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序列
- Met1-Ile349
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产品特性
- A DNA sequence encoding the Mouse DKK3 protein (Q9QUN9) (Met1-Ile349) was expressed with a C-His.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- DKK3
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背景
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Abbreviation: DKK3
Target Synonym: AW061014,C87148
Background: DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.
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分子量
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Calculated MW: 38.28 kDa
Observed MW: 60 kDa
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UniProt
- Q9QUN9
抗原
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