Cytokeratin 19 Protein (AA 80-400) (His tag)
Quick Overview for Cytokeratin 19 Protein (AA 80-400) (His tag) (ABIN7505316)
抗原
See all Cytokeratin 19 (KRT19) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 80-400
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标记
- This Cytokeratin 19 protein is labelled with His tag.
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序列
- Glu 80-Leu 400
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产品特性
- A DNA sequence encoding the Human Cytokein19 protein (P08727) (Glu 80-Leu 400) was expressed with a N-His tag.
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 106,314.67 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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背景
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Abbreviation: Cytokein19
Target Synonym: Keratin,type I cytoskeletal 19,KRT19,Keratin-19 (K19)
Background: Cytokeratin 19 (Keratin, type I cytoskeletal 19, also KRT-19, CK19 and Keratin-19) is a 40-45 kDa, acidic Class I keratin member of the intermediate filament family of proteins. Individual keratins are always expressed in tandem with a second keratin, and these are found in all epithelial cells. The class I KRT-19 heterodimerizes/polymerizes with 50-52 kDa class II KRT-8 (plus KRT-5 and -7) to form 8-10 nm filaments in epidermal stem cells, secretory gland (sweat, mammary, bile duct) simple epithelium, and neuroendocrine epidermal Merkel cells. It may represent a viable marker for skin stem cells. In skin, Cytokeratin 19 forms filaments in the fetal epithelium, and then progressively decreases with age, being virtually absent by age 17. Human Cytokeratin 19 is 400 amino acids (aa) in length. It contains an N-terminal "head" region (aa 1-79) and a subsequent "rod" region (aa 80-387), but is absent a typical C-terminal tail region. Cytokeratin 19 possesses at least 5 utilized phosphorylation sites plus one acetylated Lys residue. Based on other keratins, and the presence of an Asp at position 238, there may be caspase cleavage-generated isoforms. Full length human Cytokeratin 19 (aa 2-400) shares 82 % aa sequence identity with mouse Cytokeratin 19.
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分子量
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Calculated MW: 35.2 kDa
Observed MW: 38 kDa
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UniProt
- P08727
抗原
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