Fibronectin Protein (AA 32-230) (GST-His-Tag)
Quick Overview for Fibronectin Protein (AA 32-230) (GST-His-Tag) (ABIN7505313)
抗原
See all Fibronectin 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 32-230
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标记
- This Fibronectin protein is labelled with GST-His-Tag.
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序列
- Gln 32-Arg 230
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产品特性
- A DNA sequence encoding the Human Fibronectin protein (P02751) (Gln 32-Arg 230) was expressed with a N-GST&C-His tag.
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Fibronectin (AA 1087-1172) protein (His tag)
宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibronectin (AA 1008-1231) protein (His-IF2DI Tag)宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Fibronectin
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背景
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Abbreviation: Fibronectin
Target Synonym: Fibronectin,FN1,CIG,ED-B,FINC,FN,FNZ,GFND,GFND2,LETS,MSF
Background: Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, and organization has been associated with a number of pathologies, including cancer and fibrosis. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
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分子量
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Calculated MW: 46.78 kDa
Observed MW: 50 kDa
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UniProt
- P02751
抗原
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