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RAB5 Protein (AA 1-215) (His tag)

This Recombinant RAB5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7505252
发货至: 中国
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Quick Overview for RAB5 Protein (AA 1-215) (His tag) (ABIN7505252)

抗原

See all RAB5 (RAB5A) 蛋白
RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 1-215

    标记

    This RAB5 protein is labelled with His tag.

    序列

    Met 1-Asn 215

    产品特性

    A DNA sequence encoding the Human RAB5A protein (P20339) (Met 1-Asn 215) was expressed with a N-His&C-His tag.
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 127,054.94 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

    别名

    RAB5A

    背景

    Abbreviation: RAB5A

    Target Synonym: Ras-related protein Rab-5A,RAB5A

    Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.

    分子量

    Calculated MW: 23.54 kDa

    Observed MW: 32 kDa

    UniProt

    P20339

    途径

    Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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