Ataxin 3 Protein (ATXN3) (AA 1-370) (His tag)
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- 抗原 See all Ataxin 3 (ATXN3) 蛋白
- Ataxin 3 (ATXN3)
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-370
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Ataxin 3 protein is labelled with His tag.
- 序列
- Met 1-Lys 370
- 产品特性
- A DNA sequence encoding the Human ATXN3 protein (P54252-2) (Met 1-Lys 370) was expressed with a C-His and N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
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- Discover our top product ATXN3 蛋白
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Ataxin 3 (ATXN3) (AA 1-355) protein (His tag)
custom-made ATXN3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ataxin 3 (ATXN3) (AA 1-79) protein (GST tag)ATXN3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ataxin 3 (ATXN3) (AA 1-370) protein (GST tag)ATXN3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ataxin 3 (ATXN3) (AA 1-370) proteinATXN3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
Ataxin 3 (ATXN3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ATXN3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Ataxin 3 (ATXN3)
- 别名
- Ataxin-3 (ATXN3 产品)
- 背景
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Abbreviation: Ataxin-3,ATXN3
Target Synonym: Ataxin-3,ATXN3,Machado-Joseph disease protein1,Spinocerebellar ataxia type 3 protein
Background: Ataxin-3 is a ubiquitously expressed nuclear protein that serves as a deubiquitinating enzyme (DUB) involved in protein homeostasis and quality control, myogenesis and degradation of misfolded chaperone substrates. As a DUB, it has two distinct features. Its N-terminal Josephin domain confers cysteine protease activity to Ataxin-3 which is important for hydrolyzing ubiquitin (Ub) linkages. The second important feature is its three Ub-interacting motifs (UIMs) through which it binds Ub conjugates and ubiquitinated proteins and bring them into proximity to trim or edit specific linkages within these Ub conjugates. It binds long poly-Ub chains and trims them. However, it has weak or no activity against chains of 4 or less Ub.
- 分子量
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Calculated MW: 40.59 kDa
Observed MW: 50 kDa
- UniProt
- P54252-2
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