FABP3 Protein (AA 2-133) (His tag)
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Quick Overview for FABP3 Protein (AA 2-133) (His tag) (ABIN7504924)
抗原
See all FABP3 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 2-133
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标记
- This FABP3 protein is labelled with His tag.
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序列
- Val2-Ala133
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产品特性
- Recombinant Human Fatty Acid-Binding Protein 3 is produced by our E.coli expression system and the target gene encoding Val2-Ala133 is expressed with a 6His tag at the N-terminus.
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内毒素水平
- <1.0 EU per μg of the protein as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))
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别名
- FABP3
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背景
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Abbreviation: FABP3
Target Synonym: Fatty Acid-Binding Protein Heart,Fatty Acid-Binding Protein 3,Heart-Type Fatty Acid-Binding Protein,H-FABP,Mammary-Derived Growth Inhibitor,MDGIMuscle Fatty Acid-Binding Protein,M-FABP,FABP3,FABP11,MDGI,H-FABP,O-FABP
Background: Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. The FABP3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer. FABP3 is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of onset of pain.
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分子量
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Calculated MW: 17.0 kDa
Observed MW: 15 kDa
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UniProt
- P05413
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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