HLA-A*02:01 (AA 25-305), (Monomer) protein (His-Avi Tag,MAGE-A10)
This Recombinant protein is expressed in HEK-293 Cells.
Quick Overview for HLA-A*02:01 (AA 25-305), (Monomer) protein (His-Avi Tag,MAGE-A10) (ABIN7504370)
抗原
HLA-A*02:01
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
纯度
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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产品特性
- AA 25-305, Monomer
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标记
- His-Avi Tag,MAGE-A10
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原理
- Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Protein
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序列
- Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide
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特异性
- Uni-Prot: A0A140T913 (HLA-A*02:01), P61769 (B2M), GLYDGMEHL
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产品特性
- Recombinant Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).
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储存条件
- -80 °C
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储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- HLA-A*02:01
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背景
- MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.
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分子量
- 50.44 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.
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UniProt
- A0A140T913
抗原
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