CEACAM7 Protein (AA 36-242) (hFc Tag)
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Quick Overview for CEACAM7 Protein (AA 36-242) (hFc Tag) (ABIN7504298)
抗原
蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 36-242
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标记
- This CEACAM7 protein is labelled with hFc Tag.
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原理
- Human CEACAM-7 Protein
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序列
- Thr36-Ser242
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产品特性
- Recombinant Human CEACAM-7 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Thr36-Ser242.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human CEACAM-3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human CEACAM-7, hFc Tag with the EC50 of 26.5ng/ml determined by ELISA.,Human CEACAM-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human CEACAM-7 is greater than 95% as determined by SEC-HPLC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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缓冲液
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- CEACAM7 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7))
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别名
- CEACAM-7
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背景
- Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAM7 (CGM2), a member of the CEA family of proteins with expression restricted to the colon and pancreas, as a potential CAR T-cell target for PDAC.
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分子量
- 50.11 kDa. Due to glycosylation, the protein migrates to 68-78 kDa based on Bis-Tris PAGE result.
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UniProt
- Q14002
抗原
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