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CEACAM7 Protein (AA 36-242) (hFc Tag)

This Recombinant CEACAM7 protein is expressed in HEK-293 Cells.
产品编号 ABIN7504298
发货至: 中国
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Quick Overview for CEACAM7 Protein (AA 36-242) (hFc Tag) (ABIN7504298)

抗原

CEACAM7 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7))

蛋白类型

Recombinant

生物活性

Active

宿主

资源

  • 3
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 36-242

    标记

    This CEACAM7 protein is labelled with hFc Tag.

    原理

    Human CEACAM-7 Protein

    序列

    Thr36-Ser242

    产品特性

    Recombinant Human CEACAM-7 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Thr36-Ser242.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human CEACAM-3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human CEACAM-7, hFc Tag with the EC50 of 26.5ng/ml determined by ELISA.,Human CEACAM-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human CEACAM-7 is greater than 95% as determined by SEC-HPLC.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

    缓冲液

    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CEACAM7 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7))

    别名

    CEACAM-7

    背景

    Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAM7 (CGM2), a member of the CEA family of proteins with expression restricted to the colon and pancreas, as a potential CAR T-cell target for PDAC.

    分子量

    50.11 kDa. Due to glycosylation, the protein migrates to 68-78 kDa based on Bis-Tris PAGE result.

    UniProt

    Q14002
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