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CD47 Protein (CD47) (AA 19-139)

This Recombinant CD47 protein is expressed in HEK-293 Cells.
产品编号 ABIN7504274
发货至: 中国

Quick Overview for CD47 Protein (CD47) (AA 19-139) (ABIN7504274)

抗原

See all CD47 蛋白
CD47

蛋白类型

Recombinant

宿主

  • 35
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资源

  • 41
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HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 19-139

    原理

    Human CD47 Protein

    序列

    Gln19-Pro139

    产品特性

    Recombinant Human CD47 Protein is expressed from HEK293 without tag.It contains Gln19-Pro139.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    缓冲液

    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CD47

    别名

    CD47

    背景

    CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.

    分子量

    13.72 kDa. Due to glycosylation, the protein migrates to 35-48 kDa based on Tris-Bis PAGE result.

    UniProt

    Q08722-1
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