Rubella Virus E2 protein (His tag)
-
- 抗原
- Rubella Virus E2
- 蛋白类型
- Recombinant
- 宿主
- Rubella Virus (RuV)
-
资源
- HEK-293 Cells
- 标记
- His tag
- 原理
- Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag (HPLC-verified)
- 序列
- Gly 301- Ala 532
- 产品特性
- Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag is expressed from human 293 cells (HEK293). It contains AA Gly 301- Ala 532 (Accession # P08563).
- 纯度
- 90 %
- 内毒素水平
- 1.0 EU per μg
-
-
- 说明
-
This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 26.7 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
-
- 抗原
- Rubella Virus E2
- 别名
- Rubella virus Glycoprotein E2
- 物质类
- Viral Protein
- 背景
- Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.
- 分子量
- 26.7 kDa
-