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LTA Protein (His tag)

This Recombinant LTA protein is expressed in HEK-293 Cells.
产品编号 ABIN7488960
发货至: 中国

Quick Overview for LTA Protein (His tag) (ABIN7488960)

抗原

See all LTA 蛋白
LTA (Lymphotoxin-alpha (LTA))

蛋白类型

Recombinant

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资源

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HEK-293 Cells

纯度

90 %

质量等级

MALS verified
  • 标记

    This LTA protein is labelled with His tag.

    原理

    Human TNF-beta / Lymphotoxin-alpha Protein, His Tag (MALS verified)

    序列

    Leu 35 - Leu 205

    产品特性

    Human TNF-beta Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 35 - Leu 205 (Accession # P01374).

    内毒素水平

    1.0 EU per μg
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  • 说明

    This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 20.5 kDa. The protein migrates as 26-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    LTA (Lymphotoxin-alpha (LTA))

    别名

    TNF-beta

    物质类

    Chemical

    背景

    The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

    分子量

    20.5 kDa

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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