tau-441 (Active) 蛋白
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- 抗原
- tau-441
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 原理
- Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free (ThT active)
- 序列
- Met 1 - Leu 441
- 产品特性
- Human Tau-441 Pre-formed Fibrils, Tag Free is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8).
- 纯度
- 95 %
- 内毒素水平
- 0.05 EU per μg
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- 说明
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This protein carries no "tag". () The protein has a calculated MW of 45.8 kDa.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 50 mM Tris, 150 mM NaCl, 1 mM DTT, 1 mM EDTA, pH 7.5
- 储存条件
- -80 °C
- 储存方法
- -70°C
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- 抗原
- tau-441
- 背景
- Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
- 分子量
- 45.8 kDa
- NCBI登录号
- NP_005901
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