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tau-441 (P301L) protein (His tag)

This Recombinant protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7482544
发货至: 中国

Quick Overview for tau-441 (P301L) protein (His tag) (ABIN7482544)

抗原

tau-441

蛋白类型

Recombinant

宿主

资源

  • 4
大肠杆菌(E. Coli)

纯度

90 %
  • 产品特性

    P301L

    标记

    His tag

    原理

    Human Tau-441 / 2N4R (P301L) Protein, His Tag

    序列

    Met 1 - Leu 441

    产品特性

    Human Tau-441 (P301L), His Tag is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8 (P301L).

    内毒素水平

    1.0 EU per μg
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  • 说明

    This protein carries a polyhistidine tag at the N-terminus. (10xHis) The protein has a calculated MW of 47.8 kDa. The protein migrates as 38-66 kDa under reducing (R) condition (SDS-PAGE).

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    tau-441

    背景

    Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

    分子量

    47.8 kDa
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