tau-441 (Lys18), (Pro301Leu-Mutant) 蛋白
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- 抗原
- tau-441
- 蛋白类型
- Recombinant
- 产品特性
- Lys18, Pro301Leu-Mutant
- 宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 原理
- Human Tau-441 (K18, P301L) Protein, Tag Free (HPLC verified)
- 序列
- Gln 244 - Glu 372
- 产品特性
- Human Tau-441 (K18, P301L) Protein, Tag Free is expressed from E. coli cells. It contains AA Gln 244 - Glu 372 (Accession # P10636-8 (P301L).
- 纯度
- 95 %
- 内毒素水平
- 0.1 EU per μg
- 质量等级
- HPLC verified
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- 说明
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This protein carries no "tag". () The protein has a calculated MW of 13.8 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE).
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH 7.5
- 储存条件
- -80 °C
- 储存方法
- -70°C
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- 抗原
- tau-441
- 别名
- Tau-441
- 背景
- Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
- 分子量
- 13.8 kDa
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