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tau-441 (Lys18), (Pro301Leu-Mutant) 蛋白

HPLC verified 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant 95 %
产品编号 ABIN7488876
发货至: 中国
  • 抗原
    tau-441
    蛋白类型
    Recombinant
    产品特性
    Lys18, Pro301Leu-Mutant
    宿主
    资源
    • 4
    大肠杆菌(E. Coli)
    原理
    Human Tau-441 (K18, P301L) Protein, Tag Free (HPLC verified)
    序列
    Gln 244 - Glu 372
    产品特性
    Human Tau-441 (K18, P301L) Protein, Tag Free is expressed from E. coli cells. It contains AA Gln 244 - Glu 372 (Accession # P10636-8 (P301L).
    纯度
    95 %
    内毒素水平
    0.1 EU per μg
    质量等级
    HPLC verified
  • 说明

    This protein carries no "tag". () The protein has a calculated MW of 13.8 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE).

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH 7.5
    储存条件
    -80 °C
    储存方法
    -70°C
  • 抗原
    tau-441
    别名
    Tau-441 
    背景
    Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
    分子量
    13.8 kDa
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