APOE 蛋白
Quick Overview for APOE 蛋白 (ABIN7482445)
抗原
See all APOE 蛋白蛋白类型
宿主
资源
纯度
质量等级
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原理
- Human Apolipoprotein E / APOE4 Protein, Tag Free (MALS verified)
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序列
- Lys 19 - His 317
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产品特性
- Human APOE4 Protein, Tag Free is expressed from human 293 cells (HEK293). It contains AA Lys 19 - His 317 (Accession # P02649-1 (C130R).
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内毒素水平
- 1.0 EU per μg
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Apolipoprotein E (APOE) (AA 19-311) protein (Fc Tag)
APOE 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Apolipoprotein E (APOE) (AA 19-317) protein (Fc Tag)APOE 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Apolipoprotein E (APOE) (AA 19-311) protein (His-IF2DI Tag)APOE 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Apolipoprotein E (APOE) protein (Myc-DYKDDDDK Tag)APOE 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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说明
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This protein carries no "tag". () The protein has a calculated MW of 34.4 kDa. The protein migrates as 34-41 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- -20°C
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- APOE (Apolipoprotein E (APOE))
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别名
- Apolipoprotein E
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背景
- APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.
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分子量
- 34.4 kDa
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途径
- Regulation of Cell Size, Lipid Metabolism
抗原
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