CD47 Protein (CD47) (Biotin,Fc-Avi Tag)
Quick Overview for CD47 Protein (CD47) (Biotin,Fc-Avi Tag) (ABIN7482388)
抗原
See all CD47 蛋白蛋白类型
宿主
资源
纯度
质量等级
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标记
- This CD47 protein is labelled with Biotin,Fc-Avi Tag.
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原理
- Biotinylated Mouse CD47 Protein, Fc,Avitag™ (MALS verified)
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序列
- Gln 19 - Lys 140
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产品特性
- Biotinylated Mouse CD47 Protein, Fc,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Lys 140 (Accession # Q61735-1).
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内毒素水平
- 1.0 EU per μg
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说明
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This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,Fc , Avi) The protein has a calculated MW of 42.0 kDa. The protein migrates as 60-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
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储存条件
- -20 °C
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储存方法
- -20°C
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- CD47
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别名
- CD47
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背景
- Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
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分子量
- 42.0 kDa
抗原
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